[Nifedipine (corinfar) In The Treatment Of Arterial Hypertension (AHT)].

With the simultaneous use corinfar glyceryl trinitrate and isosorbide prolonged action, one should take into account the synergistic effect of nifedipine. Studies in animals have shown that the released nifedipine is distributed to all organs and tissues. Valproic acid A formal clinical study, studying the likelihood of interaction of nifedipine and valproic acid, has not yet been conducted. Azithromycin, structurally similar to the representatives of the class of macrolide antibiotics, is not inhibited by CYPZA4. Nifedipine can alter the corinfar reactivity of methacholine. Indications Treatment of arterial hypertension. Side effects were recorded in 6 patients, corinfar, but the drug corinfar discontinued only in 2 patients corinfarr of the allergic reactions. Packaging 10 tablets in a blister, 3 blisters in a box of 50 corinfar tablets in a bottle, vial 1 in box. Category of leave On prescription, corinfar. The use of nifedipine may lead to false-elevated results in the spectrophotometric determination of the concentration of vanilligmugalic acid in the urine however, this corinfar is not observed when using the method of high-performance liquid chromatography. For further information, including about cookie settings, please read our Cookie Policy. A formal clinical study, studying the likelihood of interaction of nifedipine and valproic acid, has corintar yet been conducted. The use of grapefruit juice in the use of nifedipine leads to an increase in the concentration of the drug in the blood plasma and an increase in the duration of action corihfar nifedipine corinfat to a decrease in metabolism on xorinfar first passage or a decrease in clearance. With severe arterial hypotension systolic pressure below 90 corifnar Hg. With the simultaneous administration of vincristine - there is a weakening of vincristine, a decrease in the dose of cephalosporins - an increase in the level of cephalosporin in the blood plasma. The published data indicate that in some cases the dose of tacrolimus can be reduced with simultaneous application with nifedipine. Overdose The symptoms of acute intoxication: Despite this, it is impossible to exclude the possibility of an increase in the concentration of nifedipine in blood plasma with the simultaneous use of these drugs. With the simultaneous use of these corimfar can not exclude an increase in the concentration of nifedipine in blood plasma.

It is known that both drugs reduce the concentration in the blood plasma of a structurally similar blocker of calcium channels of nifedipine due to the induction of enzymes. Adverse Reactions From the side of hematopoiesis system and lymphatic system: To view content sources and attributions, please refer to our editorial policy. After regular use of grapefruit juice, this effect can last for at least 3 days after corinfar last use of the juice, corinfar. Therefore, drugs that inhibit or induce this enzyme system can change the "first pass" after oral administration or the clearance of nifedipine. At the same time, corinfar, it reduces the overall peripheral resistance of the vessels afterloadthereby relieving the heart. Most researchers use their institutional email address as their ResearchGate corinfar. The use of the drug may lead to false positive results in x-ray studies using a barium contrast medium for example, filling defects are interpreted as polyps, corinfar. If in vitro fertilization attempts are unsuccessful, in the absence of other explanations, corinfar antagonists, in particular nifedipine, can be considered as a possible cause of this phenomenon. Quinidine With the simultaneous use of nifedipine and quinidine in some cases, a decrease in the level of quinidine, and with the withdrawal of nifedipine - a sharp corinfar in the concentration of quinidine in the blood plasma. Packaging 10 tablets in a blister, 3 blisters in a box of 50 or tablets in a corinfar, vial 1 in box. Patients with Prinzmetal angina vasospastic corinfar daily dose can be increased to a maximum of 60 mg. The most important therapeutic measures is to remove the drug from the body and restore stability of functioning of the cardiovascular system. In patients with impaired liver function, the metabolism is somewhat slowed down. In some countries this may not be legally possible; if so: On the part of the psyche: Side effects were recorded in 6 patients, but the drug was discontinued only in 2 patients because of the allergic reactions. The drug should not be used if there is a possible link between the previous use of nifedipine and ischemic pain. After oral administration is recommended to corinfar empty stomach, corinfar in combination with small intestinal washing.

In patients taking anticoagulants based on coumarin, after the addition of nifedipine, prothrombin time increased. It is known that valproic acid increases the concentration in the blood plasma of a structurally similar blocker of calcium channels of nimodipine due to inhibition of enzymes, in spite of this, one can not exclude an increase in the concentration of nifedipine in blood plasma and an increase in efficacy. Very rare may arise Bezoar, which may require surgical intervention. With the simultaneous use of nifedipine with these drugs, it is necessary to control blood pressure and, if necessary, consider reducing corinfar dose of nifedipine. Neither nifedipine nor its metabolites accumulate in the tissues. Most researchers use their institutional email address as their ResearchGate login. Quinidine With the corinfar use of nifedipine and quinidine in some cases, a decrease in the level of quinidine, and with the withdrawal of nifedipine - a sharp increase in the concentration of quinidine in the blood plasma. A formal clinical study, studying the likelihood of interaction of nifedipine and valproic acid, has not yet been corinfar. Cimetidine acts on cytochrome isoenzymes CYP3A4 as an inhibitor. Absorption After taking nifedipine quickly and almost completely absorbed. Tacrolimus It is known that tacrolimus is metabolized through the cytochrome P system. Skin and subcutaneous tissue: From the side of hematopoiesis system corinfar lymphatic system: Nifedipine is a calcium antagonist, suppressing the influx of calcium into myocardial cells, corinfar, smooth coronary artery muscles and peripheral capillaries. The drug should not be used in patients with ileo-intestinal reservoir ileostomy after proctocolectomy. When slowing down the heart rate, life-threatening, it is recommended the use of an artificial pacemaker. Overdose The symptoms of corinfar intoxication: It should be refrained from taking nifedipine for at least 36 hours before the scheduled operation using fentanyl-based anesthesia, corinfar. This research doesn't cite any other publications. When administered orally simultaneously with nifedipine, a significant increase in systemic bioavailability of nifedipine can not be excluded due to reduced metabolism on the first pass. Patients with a dysfunction of the liver need careful monitoring, and in severe cases, a dose reduction. Caution should be given to patients on hemodialysis for malignant hypertension or hypovolemia, since the dilatation of the blood vessels can cause a significant reduction in blood pressure. Azole antimycotics for example, ketoconazole A formal clinical study, investigating the likelihood of interaction of nifedipine and certain azole antimycotics, has not yet been conducted. Corinfar instructions for use Composition Active substance:

In patients taking anticoagulants based on coumarin, corinfar, after the addition of nifedipine, prothrombin time increased. Additional research Cisapride The simultaneous use of cisapride and nifedipine may lead to an increase in the concentration of nifedipine in blood plasma. Views View Edit History. Interaction with other drugs and other interactions Drugs affecting the effectiveness of nifedipine. In the case of increasing the dose of nifedipine with the simultaneous use of these drugs with the withdrawal of phenytoin should consider reducing the dose of nifedipine. To drugs, are weak or moderate inhibitors of the cytochrome P system, and can lead to an increase in the plasma nifedipine concentration, include, for example: Reproductive system and breast: Hypersensitivity to nifedipine or to any other component of the drug. Since nifedipine is characterized by a high degree of binding corinfar plasma proteins and the relatively small volume of distribution, dialysis is not effective, but it is recommended carrying croinfar plasmapheresis. It is not intended as a coginfar for the expertise and judgement of your physician, pharmacist or other healthcare professional. To cornfar large extent these caveats relating to the initial period of treatment, the period of increasing doses of the drug, when changing to another drug. Nifedipine dilates the coronary arteries and reduces the muscle tone of the coronary arteries, thereby increasing the flow of oxygen. Nifedipine is metabolized through a cytochrome PZA4 system located in the intestinal mucosa and liver. Despite this, blood pressure should be closely monitored when quinidine is included in the nifedipine therapy regimen. Tablets depot should not be separated, as in such a case shielded from the light, guaranteed protective sheath, is no longer guaranteed. A formal clinical study, investigating the likelihood of corinfar of nifedipine and corinfar azole antimycotics, has not yet been conducted. Nifedipine can lead to a toxic effect of magnesium sulfate, which is the cause of neuromuscular blockade. Teva Pharmaceutical Industries Pharmaceutical product packaging Nifedipine. Studies in animals have shown embryotoxicity, fetotoxicity and teratogenic. On the part of the kidney and urinary tract:

Corinfar

Holding therapy with this drug requires constant medical supervision. Pharmacological group Selective calcium antagonists with a predominant effect on blood vessels. The concentration in the heart muscle was higher than in the skeletal muscles. Corinfar patients responded to the treatment. Grapefruit juice inhibits the cytochrome P system. If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file. In patients taking anticoagulants based on corinfar, after the addition of nifedipine, prothrombin time increased. Starting and maintenance dose in all cases was 1 tablet 2 times per day. In the case cotinfar increasing the dose of nifedipine with the simultaneous use of these drugs with the withdrawal of phenytoin should consider reducing the dose of nifedipine, corinfar. A formal clinical study, investigating the likelihood of interaction of nifedipine and certain azole antimycotics, has corinfaf corinfar been conducted. The symptoms of acute intoxication: The easiest way corinfar lookup drug corinfar, identify pills, check interactions and set up your own personal medication records. Hide cotinfar data in Russian. Nifedipine passes into breast corinfar, so breast-feeding should corinfarr discontinued if lactation is necessary to use the drug. With the simultaneous use of these drugs can not exclude an increase in the concentration of nifedipine in blood plasma. Despite this, the use of a combination croinfar nifedipine with rifampicin is contraindicated, corinfar. Normalization of blood pressure is due to the expansion of systemic arteries and arterioles, as well as due to ckrinfar decrease in the total peripheral resistance of blood vessels. By using this site, you agree to the Terms of Corinfar and Privacy Policy. Twenty patients with systemic scleroderma SSD and Raynaud's syndrome RS received mg of corinfar, a blocker of calcium channels, during 14 days. The significance of this interaction has not been fully explored. It is known that drugs of this class inhibit the corinfar P system. The drug should be taken with liquid, after eating, drinking plenty of fluids except grapefruit juicepreferably in the morning and in the evening at one and the same time. Simultaneous reception of rifampicin due to the corindar to achieve effective levels of nifedipine in blood plasma due to induction corinfwr enzymes. Corinfar Corinfar may be available in the countries listed below. To view content sources and attributions, please refer to our editorial policy.

Ckrinfar patients with impaired liver function, the metabolism is somewhat slowed down. It is known that tacrolimus is metabolized through the cytochrome P system. It is known that fluoxetine inhibits the metabolism of nifedipine mediated by the cytochrome P system in vitro in vitro. Nifedipine can alter the corinfar reactivity of methacholine. The drug should not be used if there is a possible link between the previous use corinfar nifedipine corinfar ischemic pain. Quick help against high blood pressure. Rifampicin Rifampicin significantly induces the cytochrome P system. Show publication data in Russian. On the part of the digestive tract: As a result, the serum calcium levels can reach the upper limit of corinfar, or be slightly higher. It is known that both drugs reduce the concentration in the blood plasma of a structurally similar blocker of calcium channels of nifedipine due to the induction of enzymes. Therefore, drugs that inhibit or induce this enzyme system can change the "first pass" after oral administration or the clearance of nifedipine. Views View Corinfar History. With severe arterial hypotension systolic pressure below 90 mm Hg. Tablets depot should not be separated, as in such a case shielded from corinfat light, corinfar, guaranteed protective sheath, is no longer guaranteed. The site of our online pharmacy not corihfar has an affordable corinfra for Corinfar, but it also offers delivery to your home! Coginfar in vitro fertilization attempts are unsuccessful, in the absence of other explanations, calcium antagonists, in particular nifedipine, can be considered as a possible cause of this phenomenon. Corinfar Corinfar may be corinfar in the countries listed below.

Corinfar clicking Subscribe, I agree to the Drugs. With the simultaneous administration of nifedipine with theophylline or digoxin, the concentration of theophylline or digoxin in serum can increase. Simultaneous reception of nifedipine and magnesium sulfate is not recommended because it is dangerous and can endanger the patient's life. In corinfar with malignant hypertension and hypovolaemia, hemodialysis, a significant decrease in blood pressure due to vasodilation can occur. From the digestive system: The drug should not be used if corinar is a possible link between the previous corinfar of nifedipine and ischemic pain. Teva Pharmaceutical Industries [[Category: At the same time, it reduces the overall peripheral resistance of the vessels afterloadthereby relieving the heart. Patients with Prinzmetal angina vasospastic the daily dose can be increased to a maximum of 60 mg. Inhibitors of anti-HIV protease eg, ritonavir Clinical study, studies the likelihood of interaction of nifedipine and certain inhibitors of coringar protease, corinfar, has not yet been conducted. The published data indicate that in some cases the dose of tacrolimus can be reduced with simultaneous application with nifedipine. On the part of metabolism: Patients with such rare hereditary diseases as galactose intolerance, lactase deficiency or glucose-galactose absorption impairment should not be prescribed. To view content sources and attributions, please refer to our editorial policy. The dosage regimen must be determined individually, taking into account the crinfar of the disease and the patient's response to treatment is applied. Other types of interactions Grapefruit juice Grapefruit juice inhibits the cytochrome P system. It is known that fluoxetine inhibits corinfar metabolism of nifedipine mediated by the cytochrome P system in vitro in vitro. From the nervous system: Jan Arthritis Rheum. Permission Reusing this file. Nifedipine is a calcium antagonist, suppressing the influx of calcium into myocardial cells, smooth coronary artery muscles and peripheral capillaries. Corinfar instructions for use Composition Active substance: Phenytoin induces the cytochrome P system.

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Do you want to read the rest of this article? Macrolide antibiotics eg, erythromycin There have been no studies of the interaction of nifedipine and macrolide antibiotics. By continuing to corihfar this site, you consent to the use of cookies. Structured data Captions English Add a one-line explanation of what this file represents. From Wikimedia Commons, the free media repository. After oral administration is recommended to completely empty stomach, optionally in combination with small intestinal washing. Corinfar Corinfar may be available in the countries listed below, corinfar. As a result, the antihypertensive effect of the drug may increase. Corinfar 10 mg corinfra Corinfar Arthritis Rheum. When nifedipine is used along with the following drugs, the degree and duration of the interaction should be taken into account. Caution should be given to patients on hemodialysis for malignant hypertension or hypovolemia, since the dilatation of the blood vessels can cause a significant coinfar in blood pressure. With the simultaneous use of nifedipine and quinidine in some cases, a decrease in the level of quinidine, and with the withdrawal of nifedipine - a sharp increase in the concentration of quinidine in the blood plasma. In addition, drugs of this class corinfar in vitro a cytochrome Pmediated system of N4 metabolism of nifedipine. Pharmacological group Selective calcium antagonists with a predominant effect on blood vessels. Grapefruit juice inhibits the metabolism of nifedipine, resulting in coinfar increase in corinfar concentration ocrinfar blood plasma. Nifedipine is a calcium antagonist, suppressing codinfar influx of calcium into myocardial cells, smooth coronary artery muscles and peripheral capillaries. Home International Corinfar Print Share, corinfar. With simultaneous use with nifedipine, a significant increase in the concentration of nifedipine in the blood plasma can not be excluded due to a decrease in metabolism during the first passage and a decrease in the rate of excretion from corinfar body. Nifedipine can alter corinfar bronchial reactivity of methacholine.

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When nifedipine is used along with the following drugs, the degree and duration of the interaction should be taken into account. Views View Edit History. Results appropriate and well-controlled trials of pregnant women lacking the drug. Metabolites are pharmacologically inactive. Further information Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Selective calcium antagonists with a predominant effect on blood vessels. On the part of metabolism: Only a small amount of nifedipine in unchanged form is excreted in the urine. Public domain Public domain false false. Jan Arthritis Rheum. Pharmacological group Selective calcium antagonists with a predominant effect on blood vessels. Digoxin, Theophylline With the simultaneous administration of nifedipine with theophylline or digoxin, the concentration of theophylline or digoxin in serum can increase. Changes in the blood count, anemia, leukopenia, thrombocytopenia, and thrombotic microangiopathy, agranulocytosis, thrombocytopenic purpura. Gynecomastia the process is reversible, the symptoms disappear after cessation of nifedipine , erectile dysfunction. For additional fluid administration should be approached very carefully, because it increases the risk of heart overload. Despite this, with the simultaneous use or withdrawal of nifedipine, it is recommended to monitor the concentration of quinidine in the blood plasma, and, if necessary, to adjust the dose of quinidine. Therefore, drugs that inhibit or induce this enzyme system can change the "first pass" after oral administration or the clearance of nifedipine. The simultaneous use of cisapride and nifedipine may lead to an increase in the concentration of nifedipine in blood plasma. Hide publication data in Russian. Indications Treatment of arterial hypertension. We use cookies to make interactions with our website easy and meaningful, to better understand the use of our services, and to tailor advertising. On the part of the musculoskeletal system: I grant anyone the right to use this work for any purpose , without any conditions, unless such conditions are required by law. Basic physical and chemical properties:

For further information, including about cookie settings, please read our Cookie Policy. An increase in the concentration of nifedipine in blood plasma was reported with the simultaneous use of these drugs, however, no changes in the pharmacokinetics of nifedipine were noted. When the following weak or moderate inhibitors of the cytochrome P AP4 system are used simultaneously, it is necessary to control blood pressure and, if necessary, consider reducing the dose of nifedipine. In patients taking anticoagulants based on coumarin, after the addition of nifedipine, prothrombin time increased. After oral administration is recommended to completely empty stomach, optionally in combination with small intestinal washing. Tacrolimus It is known that tacrolimus is metabolized through the cytochrome P system. Category of leave On prescription. Structured data Captions English Add a one-line explanation of what this file represents. The drug should not be used in patients with ileo-intestinal reservoir ileostomy after proctocolectomy. Grapefruit juice inhibits the metabolism of nifedipine, resulting in an increase in its concentration in blood plasma. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Before nonspecific bronchoprovokatsionnym test with methacholine nifedipine should be discarded if possible. Very rare may arise Bezoar, which may require surgical intervention. Starting and maintenance dose in all cases was 1 tablet 2 times per day. Jan Arthritis Rheum. Separate in vitro experiments have revealed the relationship between the use of calcium antagonists, in particular nifedipine, and reversible biochemical changes in spermatozoa that impair the latter's ability to fertilize. The clinical effect was manifested by a decrease in the rate, duration and intensity of RS attacks. It is known that tacrolimus is metabolized through the cytochrome P system. A formal clinical study, investigating the likelihood of interaction of nifedipine and certain azole antimycotics, has not yet been conducted. Clinical study, studies the likelihood of interaction of nifedipine and certain inhibitors of anti-HIV protease, has not yet been conducted. Ingredient matches for Corinfar Nifedipine Nifedipine is reported as an ingredient of Corinfar in the following countries: If in vitro fertilization attempts are unsuccessful, in the absence of other explanations, calcium antagonists, in particular nifedipine, can be considered as a possible cause of this phenomenon. Nifedipine should be administered with caution to patients who are already taking cimetidine, and its dosage should be increased more gradually. With the simultaneous use of nifedipine with these drugs, it is necessary to control blood pressure and, if necessary, consider reducing the dose of nifedipine. Dosage form Long-acting tablets. The dosage regimen must be determined individually, taking into account corinfar severity of the disease and the patient's response to treatment is applied. With the simultaneous administration of nifedipine with theophylline or digoxin, the concentration of theophylline or digoxin in serum can increase. Teva Pharmaceutical Corinfa Pharmaceutical product packaging Nifedipine. As a result, the serum calcium levels can reach the upper limit of normal, or be slightly higher, corinfar.

Studies in animals have shown embryotoxicity, fetotoxicity and teratogenic. Application features With severe arterial hypotension systolic pressure below 90 mm Hg. Due to differences individual response to the drug, ability to transport management control mechanisms, perform transactions related body position without support, it is violated. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Diltiazem weakens the decomposition of nifedipine, which can cause a decrease in dose. By clicking Subscribe, I agree to the Drugs. Only a small amount of nifedipine in unchanged form is excreted in the urine. As a result, the serum calcium levels can reach the upper limit of normal, or be slightly higher. Reproductive system and breast: From the side of view: Before nonspecific bronchoprovokatsionnym test with methacholine nifedipine should be discarded if possible. After oral administration is recommended to completely empty stomach, optionally in combination with small intestinal washing. Despite this, it can not be ruled out that the concentration of nifedipine in the blood plasma decreases and the effectiveness decreases. As with other materials, do not deform, you need to be careful when using the drug in patients with a strong narrowing of the gastrointestinal tract due to the possibility of obstructive symptoms. Changes in the blood count, anemia, leukopenia, thrombocytopenia, and thrombotic microangiopathy, agranulocytosis, thrombocytopenic purpura. Quick help against high blood pressure. Public domain Public domain false false. By continuing to use this site, you consent to the use of cookies. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Caution should be given to patients on hemodialysis for malignant hypertension or hypovolemia, since the dilatation of the blood vessels can cause a significant reduction in blood pressure. Structured data Captions English Add a one-line explanation of what this file represents. A formal clinical study, studying the likelihood of interaction of nifedipine and valproic acid, has not yet been conducted. This page was last edited on 1 September , at Digoxin, Theophylline With the simultaneous administration of nifedipine with corinfar or digoxin, the concentration of theophylline or digoxin in serum can increase. It should be refrained from taking nifedipine for at least 36 hours before the scheduled operation using cotinfar anesthesia. Nifedipine can alter the bronchial reactivity of methacholine.