Sildenafil Actavis 25 Mg, 50 Mg And 100 Mg Film-coated Tablets

Serious cardiovascular events, including myocardial infarction, unstable angina, sudden cardiac death, ventricular arrhythmia, cerebrovascular haemorrhage, transient ischaemic attack, hypertension and hypotension have been reported post-marketing in temporal association with the use of sildenafil. Hepatic insufficiency. Sildenafil Actavis is contraindicated in patients who have loss of vision in one eye because of non-arteritic anterior ischaemic optic neuropathy NAIONsildenafil of whether this episode was in connection or not with previous PDE5 inhibitor exposure see section 4. This includes any possible side effects actavis listed in this leaflet. Visual appearance 50 mg tablets are white to off-white coloured, diamond shaped, biconvex, film coated tablets with "U" 100mg on one side and "50" debossed on other side. SmPC Patient Leaflet. Therefore the use of such combinations is not recommended. Women Sildenafil Actavis is not indicated for use by women. What you need to know before you take Sildenafil Sildenafil Do not take Sildenafil Actavis If you are allergic to sildenafil or any of the other ingredients of this medicine listed in section 6. Tabulated list of adverse reactions. Sildenafil Actavis mg film-coated tablets are blue elliptical, biconvex, The other ingredients are: Agents for the treatment of erectile dysfunction, including sildenafil, should be used with caution in patients with anatomical deformation of the penis such as angulation, cavernosal fibrosis or Peyronie's diseaseor in actavis who have conditions which may predispose them to priapism such as sickle cell anaemia, multiple myeloma or leukaemia. Sign Up Log In Cancel. If you have 100mg had a stroke or a heart attack, or if you have low blood pressure. Furthermore, as one ages, sildenafil actavis 100mg, many medical conditions that cause ED become more commonplace. The European Medicines Agency has waived the obligation to submit the results of studies with the reference medicinal product containing sildenafil in all subsets of the paediatric population for the treatment of erectile dysfunction. Patients with increased susceptibility to vasodilators include those with left ventricular outflow obstruction e. Pharmacokinetics in special patient groups.

Medinfo accord-healthcare. Actavis Group PTC ehf. Keep out of the reach and sight of children Do not use Sildenafil Actavis after the expiry date which is stated on the carton. The tablets are provided in blister packs containing 1, 2, 4, 8 or 12 tablets. After around 24 hours none of the active ingredient remains in the bodies plasma. These decreases in blood pressure are consistent with the vasodilatory effects of sildenafil, probably due to increased sildenafil levels in vascular smooth muscle. The safety and efficacy of sildenafil of sildenafil actavjs other treatments for erectile dysfunction have not been studied. Marketing authorisation number s 9. If you have an erection which lasts for more than 4 hours, you should contact a doctor immediately. Population pharmacokinetic analysis of clinical trial data indicated a reduction in sildenafil clearance when co-administered with CYP3A4 inhibitors such as ketoconazole, erythromycin, cimetidine. Sildenafil Actavis 50 mg tablets. Dry eye, Lacrimal disorder and Lacrimation increased Acgavis of suspected adverse reactions. Based on efficacy and tolerability, the dose may be increased step-wise to 50 mg up to mg as actavis. Find out more here. Clinical efficacy and safety Two clinical studies were specifically designed to assess the time window after dosing 100mg which sildenafil could produce an erection in 100mg to sexual stimulation. Pharmacokinetics in special patient groups. This information is intended for use by health professionals. Some pack sizes may not be marketed in your country.

Population pharmacokinetic analysis of clinical trial data sildenafil a reduction in sildenafil clearance when co-administered with CYP3A4 inhibitors such as ketoconazole, erythromycin, cimetidine. You should not take Sildenafil Actavis if you actavis not have erectile dysfunction. Actavis maximum recommended dose is mg. Studies in vitro have shown that sildenafil is selective for PDE5, which is involved in the erection process. Effect on bleeding. Find out more here. From post-marketing experience cases of unstable angina a heart condition 100mg sudden death have been reported rarely. Pharmacotherapeutic group: See 4. Take special care with Sildenafil Actavis Tell your doctor. Sildenafil metabolism is principally mediated by the cytochrome P CYP isoforms 3A4 major route and 2C9 minor route. If Sildenafil Actavis does not help you to get an erection, or if your erection does sildenafio last long enough for you to complete sexual intercourse you should tell your doctor. Non-clinical data revealed no special hazard for humans based 100mg conventional studies sildenafil silfenafil pharmacology, repeated dose toxicity, genotoxicity, carcinogenic potential, sildenafil actavis 100mg, and toxicity to reproduction and acravis. Sildenafil authorisation holder 8. Sildenafil Actavis mg film-coated tablets are blue elliptical, biconvex, Effects on vision Cases of visual defects have been reported spontaneously in connection with the intake of sildenafil and sildenaful PDE5 inhibitors see section 4. Contact your doctor if you take more tablets than you should. Possible side effects Like all medicines, this medicine can cause side effects, although not everybody gets them. This is most likely to happen within 4 hours after taking Sildenafil Actavis. Dildenafil works by helping to relax the blood vessels in your penis, allowing blood to flow into your penis when you get sexually excited. Based on efficacy and actavis, the dose may be increased step-wise to 50 mg up to mg as necessary. The major circulating metabolite results from N-demethylation of sildenafil. You should check with your doctor or pharmacist if you are 100mg sure. When sildenafil and doxazosin were administered simultaneously to patients stabilized on doxazosin therapy, there were infrequent reports of patients who ssildenafil symptomatic postural hypotension. Seizures or fits sildebafil this occurs rarely.

Co-administration of sildenafil with ritonavir is not advised see section 4. Based on these pharmacokinetic results co-administration of sildenafil with ritonavir is not advised see section 4. Because not all adverse reactions are reported the frequencies of these reactions cannot be reliably determined. If you have any further questions, ask your doctor, pharmacist or nurse. Medicines should not be disposed of via wastewater or household waste. If you feel that the effect of Sildenafil Actavis is too strong or too weak, talk to your doctor or pharmacist. Concomitant use with ritonavir. In the event of a medical emergency, you should tell actavis health care professional treating your condition that you have taken Sildenafil Actavis and when you did. Rare may affect up to 1 in 1, people: Sildenafil Actavis mg tablets. Sildenafil Actavis mg film coated Package leaflet: You should not take Sildenafil Actavis if you are a woman. Not all pack sizes may be marketed. In addition, the frequency of medically important adverse reactions reported from post-marketing experience is included as not known. A sudden decrease or sildenafil of vision - this occurs rarely Serious skin reactions - this occurs rarely Symptoms may include severe peeling and swelling of the skin, actavis of the mouth, genitals and around the eyes, fever. All gone: Please enter your sildenafil Suldenafil enter your email Your 100mg is invalid. Always take Sildenafil Actavis exactly as your doctor has told you. The safety profile of sildenafil is based on 8, patients who received the recommended dosing regimen in 67 placebo-controlled clinical studies. What you need to know before you take Sildenafil Actavis Do not take Sildenafil Actavis If you are allergic to sildenafil or any of the other ingredients of this medicine listed in section 6. However, you may find that 100mg Actavis takes longer to start working acyavis you take it with a heavy meal, sildenafil actavis 100mg. Active ingredient sildenafil citrate. Effect on bleeding. As dizziness and altered vision were reported in clinical trials with sildenafil, patients should actaviis aware of how they react to Sildenafil Actavis, before driving or operating machinery.

Sildenafil actavis 100mg

Sildenafil had no effect on saquinavir pharmacokinetics acgavis section 4. Dry eye, Lacrimal disorder and Lacrimation increased Reporting of suspected adverse reactions. Adtavis doctor should carefully check whether your heart can take the additional strain of having sex. If 100gm experience any of the following serious side effects stop taking Sildenafil Actavis and seek 100mg help immediately: If present, side effects from taking sildenafil are usually mild and may include:. You should seek medical advice in relation to medicines and use only as directed by a acyavis professional. This includes any possible side effects not listed in this leaflet. Common side effects include: To view the changes actafis a medicine you must sign up and log in. Pharmacotherapeutic group: Pooling of the following classes of antihypertensive medication: Back to top Accord-UK Ltd contact details. Patients should be advised that in the event of any sudden visual defect, they should stop taking Sildenafil Actavis and consult a physician immediately see section 4. Sildenafil had no effect on ritonavir pharmacokinetics. The mean steady state volume of distribution V d for sildenafil is l, indicating distribution into the tissues. Since sildenafil clearance is reduced in patients with hepatic impairment e. You should check with your doctor or pharmacist if you are not sure. This is most likely to occur within 4 hours post sildenafil dosing. Respiratory, thoracic sidenafil mediastinal disorders. With the exception of ritonavir for which co-administration with sildenafil is not advised see section 4. If you feel that the effect of Sildenafil Actavis is too strong or too weak, talk to your doctor or pharmacist. Do not take Sildenafil Actavis If you are taking medicines containing nitrates, as the combination may cause a potentially dangerous decrease in your blood pressure. You may find that Sildenafil Actavis takes longer to work if you sildenafil it with a heavy meal.

You should not take Sildenafil Actavis more than once a day. Pooling of the following classes of antihypertensive medication: Driving and using machines Sildenafil Actavis can cause dizziness and can affect vision. Initiation of sildenafil at a dose of 25 mg should be considered see section 4. You should not use Sildenafil Actavis with any other oral or local treatments for erectile dysfunction. In order to reduce the likelihood that these symptoms occur, you should be on a regular daily dose of your alpha-blocker before you start Sildenafil Actavis. Each tablet contains If you have a severe heart or liver problem. Contact your doctor if you take more tablets than you should. Drinking alcohol can temporarily impair your ability to get an erection. Enter medicine name or company Start typing to retrieve search suggestions. Clinical particulars 4. Prior to prescribing sildenafil, physicians should carefully consider whether 100mg patients with certain underlying conditions could be actavis affected by such vasodilatory effects, especially in combination with sexual activity. As dizziness and altered vision were reported in clinical trials with sildenafil, patients should sildehafil aware of how they atcavis to Sildenafil Actavis, before driving or operating machinery. Not all pack sizes may be marketed. You can also report side effects directly via. Therefore sildenafil should be administered to these patients only after careful benefit-risk assessment, sildenafil actavis 100mg. Clinical efficacy and safety. Nicorandil is a hybrid sjldenafil potassium actavls activator and nitrate. Concomitant use with ritonavir Co-administration of sildenafil with ritonavir is not acatvis see section 4.

To get the maximum benefit from your medicine, you are advised not to drink excessive amounts of alcohol before taking Sildenafil Actavis. Renal insufficiency. It should be noted that sexual stimulation is required for an erection to occur, and some patients may actavis respond to the starting dose of 50mg, in which case their doctor may increase the dosage. In order to minimise the potential of developing postural hypotension in patients receiving alpha-blocker treatment, patients should be stabilised on alpha-blocker therapy prior to initiating 100mg treatment, sildenafil actavis 100mg. This sildenafil is available from a pharmacist and requires a prescription. Concomitant use with other PDE5 inhibitors or other treatments for erectile dysfunction. Maximum observed plasma concentrations are reached within 30 to minutes median 60 minutes of oral dosing in the fasted state. The other ingredients are: The medicine can only be obtained with sjldenafil prescription. Hypersensitivity to the active substance actavis to any of the excipients listed in section 100mg. It may harm them, even if their signs of illness actavvis the same as yours. Agents for the treatment of erectile dysfunction, including sildenafil, should not be used sildenafil men for whom sexual activity is inadvisable e. In order to reduce the likelihood that these symptoms occur, you should be on a regular daily dose of your alpha-blocker before you start Sildenafil Actavis. Single oral doses of sildenafil up to mg in healthy volunteers produced no clinically relevant effects on ECG. Not all pack sizes may be marketed.

What is in sildenafil?

Prior to initiating any treatment for erectile dysfunction, physicians should consider the cardiovascular status of their patients, since there is a degree of cardiac risk associated with sexual activity. Each tablet contains Renal insufficiency. Sildenafil Actavis is contraindicated in patients who have loss of vision in one eye because of non-arteritic anterior ischaemic optic neuropathy NAIONregardless of whether this episode was in connection or not with 100mg PDE5 inhibitor exposure see section 4. Cases of visual defects have been reported 100mg in actavis with the intake of sildenafil and other PDE5 inhibitors see section 4. See section 4. Sildenafil Actavis is a medicine that contains sildenafil active substance sildenafil. Hepatic insufficiency. Last updated on sjldenafil Medinfo accord-healthcare. How is it used? Use in patients taking other medicinal products. They can help you balance the risks actavis the benefits of this medicine acgavis pregnancy, sildenafil actavis 100mg. Cases of non-arteritic anterior ischaemic optic neuropathy, a rare condition, have been reported sildenaafil and in an observational study in connection with the intake of sildenafil and other PDE5 inhibitors see section 4. After around 24 hours none of the active ingredient remains in the bodies plasma. During normal sexual stimulation, cGMP is produced in the penis, where it causes the muscle in the spongy tissue of the penis the corpora cavernosa to relax. Do I need a prescription? Name of the medicinal product 2. What Sildenafil Actavis looks like and contents of the pack Film-coated tablet. Drinking alcohol can temporarily impair the ability to get an erection. In sildenafil, initiation of sildenafil at a dose of 25 mg should be considered see sections 4.

Not all pack sizes may be marketed. Marketing authorisation number s Sildenafil Actavis 25 mg film-coated tablets. This site uses cookies. This is required. As dizziness and altered vision were reported in clinical trials with sildenafil, patients should be aware of how they react to Sildenafil Actavis, before driving or operating machinery. Other medicines and Sildenafil Actavis Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. Paediatric population. Actavis Group PTC ehf. You should not take Sildenafil Actavis more than once a day. Musculoskeletal and connective tissue disorders. The amount of time Sildenafil Actavis takes to work varies from person to person, but it normally takes between half an hour and one hour. No studies on the effects on the ability to drive and use machines have been performed. After around 24 hours none of the active ingredient remains in the bodies plasma. The physiological mechanism responsible for erection of the penis involves the release of nitric oxide NO in the corpus cavernosum during sexual stimulation. Pharmaceutical form Film-coated tablet. Therefore sexual stimulation is required in order for sildenafil to produce its intended beneficial pharmacological effects. Mechanism of action.

Who should take sildenafil?

If you are taking medicines called nitrates, as the combination may lead to a dangerous fall in your blood pressure. The safety of sildenafil has not been studied in the following sub-groups of patients and its use is therefore contraindicated: The active substance is sildenafil. Your doctor may start you on a lower dose 25 mg of Sildenafil Actavis. In clinical trials sildenafil was administered to more than patients aged Tell your doctor if you are taking any of these medicines which are often given for relief of angina pectoris or? To bookmark a medicine you must sign up and log in. If you experience a sudden decrease or loss of vision, stop taking the medicinal product and contact your doctor immediately. Nicorandil is a hybrid of potassium channel activator and nitrate. If you have a severe heart or liver problem. Its effect is more potent on PDE5 than on other known phosphodiesterases. Priapism Agents for the treatment of erectile dysfunction, including sildenafil, should be used with caution in patients with anatomical deformation of the penis such as angulation, cavernosal fibrosis or Peyronie's disease , or in patients who have conditions which may predispose them to priapism such as sickle cell anaemia, multiple myeloma or leukaemia. The Sildenafil Actavis tablet contains lactose monohydrate. Hypersensitivity to the active substance or to any of the excipients listed in section 6. In healthy male volunteers, sildenafil at steady state 80 mg t. Therefore the use of such combinations is not recommended. Rare may affect up to 1 in 1, people: See 4. Concomitant use with other PDE5 inhibitors or other treatments for erectile dysfunction The safety and efficacy of combinations of sildenafil with other PDE5 inhibitors, or other pulmonary arterial hypertension PAH treatments containing sildenafil REVATIO , or other treatments for erectile dysfunction have not been studied.

For oral use. Protein binding is independent of total drug concentrations. Your doctor may decide on a lower dose for you. Date of revision of the text 06 July Detailed information on this medicinal product is available on the website of the European Medicines Agency http: In order to minimise the potential of developing postural hypotension in patients receiving alpha-blocker treatment, patients should be stabilised on alpha-blocker therapy prior to initiating sildenafil treatment. You should not take Sildenafil Actavis more than once a day. This is required. Hepatic insufficiency. Two clinical studies were specifically designed to assess the time window after dosing during which sildenafil could produce an erection in response to sexual stimulation. If you have any further questions, ask your doctor, pharmacist or nurse. After oral dosing of sildenafil AUC and C max increase in proportion with dose over the recommended dose range mg. The medicine can only be obtained with a prescription. To view the changes to a medicine you must sign up and log in. The recommended starting dose is 50 mg. Prescription only medicine. In clinical studies, riociguat has been 100mg to augment the hypotensive effects of PDE5 inhibitors. To get the maximum benefit actavis your medicine, you are advised not to drink 100mg amounts of alcohol before taking Sildenafil Actavis. In actavis specific drug-drug interaction studies, sildenafil alpha-blocker doxazosin 4 mg and 8 mg and sildenafil 25 mg, 50 mg, or mg were administered simultaneously to patients with benign prostatic hyperplasia BPH stabilized on doxazosin therapy. Marketing authorisation sildenafil s 9. Generic sildenafil contains the active ingredient sildenafil citrate. Send to: Though specific questions or concerns should always be discussed with a doctor, it never hurts to be informed about any medicine you are thinking of taking.

Please check and try again Please enter recipient's email Recipient's email is invalid. Pharmaceutical particulars 6. Patients with increased susceptibility to vasodilators include those with left ventricular outflow obstruction e. Still effective?: However, due to high inter-subject variability, these differences were not statistically significant. Patients with liver problems or severe kidney problems should start treatment with the mg dose. Renal dialysis is not expected to accelerate clearance as sildenafil is highly bound to plasma proteins and not eliminated in the urine. Further information on brands of sildenafil and generic medicines FAQs. Posology Use in adults The recommended dose is 50 mg taken as needed approximately one hour before sexual activity. Absorption Sildenafil is rapidly absorbed. Continue typing to refine. Sildenafil should be taken approximately 40 minutes before sexual intercourse, and two hours after a meal. The amount of time Sildenafil Actavis takes to work varies from person to person, but it normally takes between half an hour and one hour. Headache very common Dizziness Visual colour distortions blue vision , visual disturbance, blurred vision Flushing, hot flushes Nasal congestion Nausea, Dyspepsia indigestion Though it is rare, patients are advised to seek medical attention immediately if they experience any signs of an allergic reaction such as swelling of the face, lips, tongue, or throat, difficulty breathing, or hives. Find out more here. Sildenafil had no effect on saquinavir pharmacokinetics see section 4. Pharmacological properties 5. If you have chest pains during or after intercourse: Those seeking a longer-acting tablet may benefit from Spedra avanafil , Levitra vardenafil , or Cialis tadalafil , the latter of which has a duration of up to 36 hours and is often referred to as the weekend pill. Due to the nitrate component it has the potential to result in a serious interaction with sildenafil. Patients with increased susceptibility to vasodilators include those with left ventricular outflow obstruction e. Keep out of the reach and sight of children Do not use Sildenafil Actavis after soldenafil expiry date which is stated on the carton. Sildenafil Actavis mg film-coated tablets.